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Orthomolecular Library
Links to 5233 Pubmed-abstracts of human studies

Orthomolecular selection criteria; categorized on illnesses
58 Abstracts

Cholesterol,

2004 - Dreier JP, Endres M. Statin-associated rhabdomyolysis triggered by grapefruit consumption. Neurology 2004; 62(4):670  


2004 - Ludvik B, Neuffer B, Pacini G. Efficacy of Ipomoea batatas (Caiapo) on diabetes control in type 2 diabetic subjects treated with diet. Diabetes Care 2004; 27(2):436-40  


2004 - Ros E, Nunez I, Perez-Heras A, Serra M, Gilabert R, Casals E, Ros E, Nunez I, Perez-Heras A, Serra M, Gilabert R, Casals E, Deulofeu R. A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial. Circulation 2004; 109(13):1609-14  


2003 - Davies MJ, Judd JT, Baer DJ, Clevidence BA, Paul DR, Edwards AJ, Wiseman SA, Muesing RA, Chen SC. Black tea consumption reduces total and LDL cholesterol in mildly hypercholesterolemic adults J Nutr. 2003; 133(10):3298S-3302S  


2003 - Engler MM, Engler MB, Malloy MJ, Chiu EY, Schloetter MC, Paul SM, Stuehlinger M, Lin KY, Cooke JP, Morrow JD, Ridker PM, Rifai N, Miller E, Witztum JL, Mietus-Snyder M. Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation 2003; 108(9):1059-63.  


2003 - Kawano H, Yasue H, Kitagawa A, Hirai N, Yoshida T, Soejima H, Miyamoto S, Nakano M, Ogawa H. Dehydroepiandrosterone supplementation improves endothelial function and insulin sensitivity in men. J Clin Endocrinol Metab 2003; 88(7):3190-5  


2003 - Jenkins DJ, Kendall CW, Marchie A, Faulkner DA, Wong JM, de Souza R, Emam A, Parker TL, Vidgen E, Lapsley KG, Trautwein EA, Josse RG, Leiter LA, Connelly PW. Effects of a dietary portfolio of cholesterol-lowering foods vs lovastatin on serum lipids and C-reactive protein. JAMA 2003;290(4):502-10 Redactioneel: Anderson JW. Diet first, then medication for hypercholesterolemia JAMA. 2003;290(4):531-3.  


2003 - Laidlaw M, Holub BJ. Effects of supplementation with fish oil-derived n-3 fatty acids and gamma-linolenic acid on circulating plasma lipids and fatty acid profiles in women. Am J Clin Nutr 2003; 77(1):37-42  


2003 - Besler HT, Comoglu S. Lipoprotein oxidation, plasma total antioxidant capacity and homocysteine level in patients with multiple sclerosis. Nutr Neurosci 2003; 6(3):189-96  


2003 - Hays JH, DiSabatino A, Gorman RT, Vincent S, Stillabower ME Effect of a high saturated fat and no-starch diet on serum lipid subfractions in patients with documented atherosclerotic cardiovascular disease. Mayo Clin Proc 2003; 78(11):1331-6  


2003 - Lamarche B, St-Pierre AC, Ruel IL, Cantin B, Dagenais GR, Despres JP. A prospective, population-based study of low density lipoprotein particle size as a risk factor for ischemic heart disease in men. Can J Cardiol 2001; 17: 859-65  


2003 - Jenkins, D J Kendall, C W D'Costa, M A Jackson, C J Vidgen, E Singer, W Silverman, J A Koumbridis, G Honey, J Rao, A V Fleshner, N Klotz, L. Soy consumption and phytoestrogens: effect on serum prostate specific antigen when blood lipids and oxidized low-density lipoprotein are reduced in hyperlipidemic men. J Urol 2003; 169(2): 507-11  


2003 - Dallongeville J, Yarnell J, Ducimetiere P, Arveiler D, Ferrieres J, Montaye M, Luc G, Evans A, Bingham A, Hass B, Ruidavets JB, Amouyel P. Fish consumption is associated with lower heart rates. Circulation 2003; 108(7):820-5  


2003 - Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003; 26(12):3215-8  


2002 - Desideri G, Marinucci MC, Tomassoni G, Masci PG, Santucci A, Ferri C. Vitamin E supplementation reduces plasma vascular cell adhesion molecule-1 and von Willebrand factor levels and increases nitric oxide concentrations in hypercholesterolemic patients. J Clin Endocrinol Metab 2002 Jun;87(6):2940-2945  


2002 - Jula A, Marniemi J, Huupponen R, Virtanen A, Rastas M, Ronnemaa T. Effects of diet and simvastatin on serum lipids, insulin, and antioxidants in hypercholesterolemic men: a randomized controlled trial. JAMA 2002; 287:598-605.  


2002 - Wink J, Giacoppe G, King J. Effect of very-low-dose niacin on high-density lipoprotein in patients undergoing long-term statin therapy. Am Heart J 2002;143(3):514-518.  


2002 - Gouni-Berthold I, Berthold HK. Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent. Am Heart J 2002; 143(2):356-365  


2002 - Jenkins DJ, Kendall CW, Jackson CJ, Connelly PW, Parker T, Faulkner D, Vidgen E, Cunnane SC, Leiter LA, Josse RG. Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women. Am J Clin Nutr 2002; 76(2):365-372  


2002 - Grundy SM, Vega GL, McGovern ME, Tulloch BR, Kendall DM, Fitz-Patrick D, Ganda OP, Rosenson RS, Buse JB, Robertson DD, Sheehan JP; Diabetes Multicenter Research Group. Efficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan trial. Arch Intern Med 2002; 162(14):1568-1576  


2002 - Jenkins DJ, Kendall CW, Faulkner D, Vidgen E, Trautwein EA, Parker TL, Marchie A, Koumbridis G, Lapsley KG, Josse RG, Leiter LA, Connelly PW. A dietary portfolio approach to cholesterol reduction: combined effects of plant sterols, vegetable proteins, and viscous fibers in hypercholesterolemia. Metabolism 2002; 51(12):1596-1604  


2002 - Lovejoy JC, Most MM, Lefevre M, Greenway FL, Rood JC. Effect of diets enriched in almonds on insulin action and serum lipids in adults with normal glucose tolerance or type 2 diabetes. Am J Clin Nutr 2002; 76(5):1000-1006  


2001 - Cheung MC, Zhao XQ, Chait A, Albers JJ, Brown BG. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL.Arterioscler Thromb Vasc Biol. 2001; 8:1320-6  


2001 - Fuentes F, Lopez-Miranda J, Sanchez E, Sanchez F, Paez J, Paz-Rojas E, Marin C, Gomez P, Jimenez-Pereperez J, Ordovas JM, Perez-Jimenez F. Mediterranean and low-fat diets improve endothelial function in hypercholesterolemic men. Ann Intern Med. 2001; 134(12):1115-9.  


2001 - Merchant RE, Andre CA. A review of recent clinical trials of the nutritional supplement Chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis. Altern Ther Health Med 2001; 7(3):79-91  


2000 - Goodfellow J, Bellamy MF, Ramsey MW, Jones CJ, Lewis MJ. Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia. J Am Coll Cardiol. 2000 Feb;35(2):265-70.  


2000 - Vuorio AF. et al. Stanol ester margarine alone and with simvastatin lowers serum cholesterol in families with familial hypercholesterolemia caused by the FH-North Karelia mutation. Arterioscler Thromb Vasc Biol. 2000; 20(2):500-6.  


2000 - Anderson JW, Allgood LD, Lawrence A, Altringer LA, Jerdack GR, Hengehold DA, Morel JG. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials. Am J Clin Nutr. 2000; 71(2):472-9  


2000 - Anderson JW, et al. American Journal of Clinical Nutrition 2000; 71(6):1433-1438  


2000 - Walsh K, et al. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. Nature Medicine September, 2000; 6:965-966, 1004-1010  


1999 - Chait A, Malinow MR, Nevin DN, Morris CD, Eastgard RL, Kris-Etherton P, Pi-Sunyer FX, Oparil S, Resnick LM, Stern JS, Haynes RB, Hatton DC, Metz JA, Clark S, McMahon M, Holcomb S, Reusser ME, Snyder GW, McCarron DA. Increased dietary micronutrients decrease serum homcysteine concentrations in patients at high risk of cardiovascular disease. American Journal of Clinical Nutrition 1999; 70:881-887  


1998 - McCrindle B. W. et al. Garlic extract therapy in children with hypercholesterolemia. Arch Pediatr Adolesc Med.1998;152:1089-1094.  


1998 - Bowen HT, Omaye ST. Oxidative changes associated with b-carotene and a-tocopherol enrichment of human low-density lipoproteins. J Am Coll Nutr. 1998; 17(2):171-9.  


1998 - Watson K.E. et al. Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation 1997;96:1755-1760  


1998 - Theilmeier G. et al. Adhesiveness of mononuclear cells in hypercholesterolemic humans is normalized by dietary L-arginine. Arteriosclerosis, Thrombosis, and Vascular Biology 1997;17:3557-3564.  


1998 - Ribalta J et al. Low plasma vitamin A concentrations in familial combined hyperlipidemia. Clinical Chemistry 1997;43:2379-2383.  


1998 - Davidson MH et al. Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: A randomized, doubleblind, placebo-controlled trial. Journal of the American College of Nutrition 1997;16(3):236-243.  


1998 - Heikkinen A et al. Long-term vitamin D3 supplementation may have adverse effects on serum lipids during postmenopausal hormone replacement therapy. European Journal of Epidemiology 1997;137:495-502.  


1998 - Kontush A et al. Plasma ubiquinol-10 is decreased in patients with hyper-lipidaemia. Atherosclerosis 1997;129(1992):119-126.  


1998 - Adler A.J. en Holub B.J. Effect of garlic and fish-oil on serum lipid and lipoprotein concentrations in hypercholesterolemic men. American Journal of Clinical Nutrition 1997;65:445-450.  


1997 - American Journal of Clinical Nutrition 1996;63:184-193.  


1997 - American Journal of Clinical Nutrition 1996;63:377-385.  


1997 - Simons LA et al. What dosis of vitamine E is required to reduce susceptibility of LDL to oxidation? Australian & New Zealand Journal of Medicine 1996;26:496-503.  


1997 - American Journal of Clinical Nutrition 1996;63:96-102.  


1997 - Gatto LM et al. Ascorbic acid induces a favorable lipoprotein profile in women. Journal of the American College of Nutrition 1996;15(2):154-158.  


1997 - Steiner M et al. A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids. American Journal of Clinical Nutrition 1996;64:866-70.  


1997 - Louheranta AM et al. Linoleic acid intake and susceptibility of very-low-density and low-density lipoproteins to oxidation in men. Am J Clin Nutr 1996;63:698-703.  


1997 - Rifici VA et al. Effects of dietary vitamin C and E supplementation on the copper mediated oxidation of HDL and on HDL mediated cholesterol efflux. Atherosclerosis 1996;127:19-26.  


1996 - Luoma PV et al. High serum alfa-tocopherol, albumin, selenium and cholesterol and low mortality from coronary heart disease in northern Finland. Journal of Internal Medicine 1995;237(1):49-54.  


1996 - Glueck CJ et al. Evidence that homocysteine is an independent risk factor for atherosclerosis in hyperlipidemic patients. American Journal of Cardiology 1995;75:132-136.  


1996 - Paolisso G et al. Chronic intake of pharmacological doses of vitamin E might be useful in the therapy of elderly patients with coronary heart disease. American Journal of Clinical Nutrition 1995;61:848-85.  


1996 - Anderson JW et al. Meta-analysis of the effects of soy protein intake on serum lipids. New England Journal of Medicine 1995;333:276-282.  


1995 - Am.J.Epidemiol,139,1994:­1180-1189  


1995 - Seelig M S.American Journal Clinical Nutrition 1994;13(2):116-117.  


1995 - Young, Stephen G., et al, Western Journal of Medicine 1994;160:153-164.  


1995 - Magnesium Research 1994;7(1):43-47  


1995 - McKenny, J.M., et al, JAMA 1994;271(9):672-677.  


1995 - Chait, Alan, M.D., Western Journal of Medicine 1994;160(2):183-184.