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Orthomolecular Library
Links to 5156 Pubmed-abstracts of human studies

Orthomolecular selection criteria; categorized on illnesses

48 Abstracts

Alzheimer

2007 - Luchsinger JA, Tang MX, Miller J, Green R, Mayeux R. Relation of higher folate intake to lower risk of Alzheimer disease in the elderly. Arch Neurol 2007; 64(1):86-92

2007 - Gao S, Jin Y, Hall KS, Liang C, Unverzagt FW, Ji R, Murrell JR, Cao J, Shen J, Ma F, Matesan J, Ying B, Cheng Y, Bian J, Li P, Hendrie HC. Selenium Level and Cognitive Function in Rural Elderly Chinese. Am J Epidemiol 2007; 165(8):955-65

2007 - Freund-Levi Y, Basun H, Cederholm T, Faxén-Irving G, Garlind A, Grut M, Vedin I, Palmblad J, Wahlund LO, Eriksdotter-Jönhagen M. Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms. Int J Geriatr Psychiatry 2007 Jun 21; [Epub ahead of print]

2006 - Kuriyama S, Hozawa A, Ohmori K, Shimazu T, Matsui T, Ebihara S, Awata S, Nagatomi R, Arai H, Tsuji I. Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project 1. Am J Clin Nutr 2006; 83(2):355-61

2006 - Dai Q, Borenstein AR, Wu Y, Jackson JC, Larson EB. Fruit and vegetable juices and Alzheimer's disease: the Kame Project. Am J Med 2006; 119(9):751-9.

2006 - Hartman RE, Shah A, Fagan AM, Schwetye KE, Parsadanian M, Schulman RN, Finn MB, Holtzman DM. Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease. Neurobiol Dis 2006; 24(3):506-15

2006 - Fujioka K, Greenway F, Sheard J, Ying Y. The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome. J Med Food 2006; 9(1):49-54

2006 - Tettamanti M, Garri MT, Nobili A, Riva E, Lucca U. Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus study. J Am Coll Nutr 2006; 25(6):502-8

2006 - Aycicek A, Erel O, Kocyigit A, Selek S, Demirkol MR. Breast milk provides better antioxidant power than does formula. Nutrition 2006; 22(6):616-9.

2006 - Faria-Neto JR, Chagas AC, Bydlowski SP, Lemos Neto PA, Chamone DA, Ramirez JA, da Luz PL. Hyperhomocystinemia in patients with coronary artery disease. Braz J Med Biol Res 2006; 39(4):455-63.

2006 - Weber CA, Ernst ME. Antioxidants, supplements, and Parkinson's disease. Ann Pharmacother 2006; 40(5):935-8.

2003 - Engelhart MJ, Geerlings MI, Ruitenberg A, Van Swieten JC, Hofman A, Witteman JC, Breteler MM. Diet and risk of dementia: Does fat matter?: The Rotterdam Study. Neurology 2002; 59(12):1915-1921

2003 - Aisen PS, Egelko S, Andrews H, Diaz-Arrastia R, Weiner M, DeCarli C, Jagust W, Miller JW, Green R, Bell K, Sano M. A pilot study of vitamins to lower plasma homocysteine levels in Alzheimer disease. Am J Geriatr Psychiatry 2003; 11(2):246-9

2003 - Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, Bornmann WG, Clarkson B, Xu H, Greengard P. Gleevec inhibits {beta}-amyloid production but not Notch cleavage. Proc Natl Acad Sci U S A 2003; 100(21): 12444-12449. Epub 2003 Oct 01

2003 - Klatte ET, Scharre DW, Nagaraja HN, Davis RA, Beversdorf DQ. Combination therapy of donepezil and vitamin E in Alzheimer disease. Alzheimer Dis Assoc Disord 2003; 17(2):113-6

2003 - Tildesley NT, Kennedy DO, Perry EK, Ballard CG, Savelev S, Wesnes KA, Scholey AB. Salvia lavandulaefolia (Spanish Sage) enhances memory in healthy young volunteers Pharmacol Biochem Behav 2003; 75(3):669-74

2003 - Luchsinger, J A Tang, M X Shea, S Mayeux, R. Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol 2003; 60(2): 203-8

2003 - Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol 2003; 60(7):940-6

2002 - Couzin J. Protein structure. Harmless proteins twist into troublemakers. Science. 2002; 296:28-9

2002 - Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, Breteler MM. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA 2002; 287(24):3223-3229

2002 - Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA 2002; 287(24):3230-3237

2002 - Ballard CG, O'Brien JT, Reichelt K, Perry EK. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa. J Clin Psychiatry 2002; 63(7):553-558

2002 - Barberger-Gateau P, Letenneur L, Deschamps V, Peres K, Dartigues JF, Renaud S. Fish, meat, and risk of dementia: cohort study. BMJ 2002; 325(7370):932-933

2002 - Squitti R, Lupoi D, Pasqualetti P, Dal Forno G, Vernieri F, Chiovenda P, Rossi L, Cortesi M, Cassetta E, Rossini PM. Elevation of serum copper levels in Alzheimer's disease. Neurology 2002; 59(8):1153-1161

2002 - Atamna H, Killilea DW, Killilea AN, Ames BN. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. Proc Natl Acad Sci U S A. 2002 12; 99(23):14807-12

2002 - Huang W, Qiu C, Winblad B, Fratiglioni L. Alcohol consumption and incidence of dementia in a community sample aged 75 years and older. J Clin Epidemiol 2002; 55(10):959-964

2002 - Laurin D, Foley DJ, Masaki KH, White LR, Launer LJ. Vitamin E and C supplements and risk of dementia. JAMA 2002; 288(18):2266-2268

2001 - Adair JC, Knoefel JE, Morgan N. Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease. Neurology 2001;57(8):1515-1517

2001 - Poeggeler B, Miravalle L, Zagorski MG, Wisniewski T, Chyan YJ, Zhang Y, Shao H, Bryant-Thomas T, Vidal R, Frangione B, Ghiso J, Pappolla MA. Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide. Biochemistry 2001; 40:14995-15001

2001 - Correa Leite ML, Nicolosi A, Cristina S, Hauser WA, Nappi G. Nutrition and cognitive deficit in the elderly: a population study. European Journal of Clinical Nutrition 2001; 55(12):1053-1058

2001 - Kontush A, Mann U, Arlt S, Ujeyl A, Luhrs C, Muller-Thomsen T, Beisiegel U. Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease. Free Radic Biol Med 2001; 31(3):345-54

2000 - Masaki, KH et al. Association of vitamin E and C supplement use with cognitive function and dementia in elderly men Neurology 54:1265-1272 2000

2000 - Snowdon DA, et al. Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun Study, Am J Clin Nutrit, 71:993-998 2000

2000 - Winston JL, Stewart JT. Oral therapy for cobalamin deficiency. JAGS 2000; 48:1021-1022

1999 - Malinow MR, Bostom AG, Krauss RM. Homocyst(e)ine, diet, and cardiovascular diseases: a statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation, 1999; 99:178-182

1999 - Rogers M.A., Simon D.G. A preliminary study of dietary aluminium intake and risk of Alzheimer's disease. Age and Ageing 1999;28:205-209

1998 - Joseph, J. A. et al. Long-term dietary strawberry, spinach or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J Neuroscience 1998; 18;19:8047-8055

1998 - Morris, M. C. et al. Vitamin E and vitamin C supplement use and risk of incident Alzheimer disease. Alzheimer Disease and Associated Disorders 1998; 12;3:121-126

1998 - Joosten E et al. Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients with Alzheimer's disease. Journal of Gerontology: Medical Sciences 1997;52A:M76-M79.

1998 - Kalmijn S et al. Dietary fat intake and the risk of incident dementie in the Rotterdam study. Ann Neurol 1997;42:776-782.

1997 - Barak Y et al. Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial. Prog Neuro? Psychopharmacol.& Biol.Psychiat.1996;20:729-735.

1997 - Warsama Jama J. et al. Dietary Antioxidants and cognitieve function in a population-based sample of older persons. The Rotterdam Study. American Journal of Epidemiology 1996;144(3):275-279.

1996 - Lemke M. Plasma magnesium decrease and altered calcium/magnesium ratio in severe dementia of the Alzheimer type. Biological Psychiatry 1995;37:341-343.

1996 - Pettegrew JW et al. Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease. Neurobiology of aging 1995;16(1):1-4.

1995 - Basun H. et al. Journal of the American Geriatrics Society 1994;42:132-136.

0 - Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev MeD 2007; 32(3):210-6